The weight-loss drug phentermine (which is chemically similar to amphetamine) was originally approved for use in the 1950s and 1960s, but it was never really taken off the market due to issues with abuse. That is, people would often go above and beyond the recommended dose, which in turn led to more health problems. Although, in some instances, phentermine had serious side effects, such as high blood pressure, cardiac arrest, or death, the drug has proven to be incredibly effective at helping people shed off extra pounds and prevent obesity-related health problems.
Phentermine Has One Of The Highest Approved Doses
Based on the available clinical trial data, it seems that phentermine’s highest approved dose is 16 mg. This means that the recommended starting dose for the drug is 12.5 mg. After you start taking this dose, you should expect to lose around 2.2 pounds in the first week and then 0.7 to 1.1 pounds per week in the following weeks. At this point, you would need to continue taking the medication for at least 4 weeks to start seeing weight loss benefits. Some patients have even reported losing up to 5 pounds in the first week of treatment and 1 to 2 pounds per week thereafter.
No Longer Approved For Use
Although originally approved for use in the United States in the 1950s and 1960s, phentermine did not achieve widespread popularity until later in the decade. In 1966, a U.S. National Institute of Health report found that it was one of the most effective drugs in the treatment of obesity, noting that it worked in around 75% of patients who tried it. In the 1970s, physicians would often prescribe the medication to help patients control appetite and prevent obesity-related health problems, such as heart disease and type 2 diabetes. In fact, around this time, it was even approved for use in the treatment of sleep apnea, a serious sleep disorder where breathing is disrupted during sleep. In the 1980s, the FDA began to hear more reports of cardiovascular complications, such as abnormal heart rhythms and high blood pressure. This led to the drug’s removal from the market in the United States in 1987. Although, the medication was approved for use in the United States until 2004, it is no longer recommended for use due to its potential side effects. Instead, physicians are now opting to prescribe diet pills and exercise to their patients.
Phentermine Is Still Available For International Use
While the medication was once popularly available in the United States for use in the treatment of obesity, it never really took off in other countries. This is likely because it was too readily available in the States and people there began to abuse it. That is, patients would sometimes go above and beyond the recommended dose, which resulted in more severe side effects. It is still available for use in Canada, Mexico, and parts of Europe, where it is prescribed for the treatment of obesity. However, it is important to note that since phentermine was taken off the market in the United States, countries where it is still available have changed the labeling to indicate that the drug should no longer be used there.
In summary, the drug phentermine has one of the highest approved doses of any medication available, which makes it an attractive option for weight loss. However, since it was taken off the market in the United States due to safety concerns, people in other countries where it is still available should consult their doctors before using this medication.